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Oncostatin M Protein (OSM)

This Recombinant Oncostatin M protein is expressed in 大肠杆菌（E. Coli）.

产品编号 ABIN7520374

发货至: 中国

Quick Overview for Oncostatin M Protein (OSM) (ABIN7520374)

抗原

See all Oncostatin M (OSM) 蛋白

Oncostatin M (OSM)

蛋白类型

Recombinant

生物活性

Active

宿主

人

资源

大肠杆菌（E. Coli）

纯度

> 95 % by SDS-PAGE.

Discover our top product OSM 蛋白

原理

Active Recombinant Human Oncostatin-M/OSM Protein

序列

AAIGSCSKEY RVLLGQLQKQ TDLMQDTSRL LDPYIRIQGL DVPKLREHCR ERPGAFPSEE TLRGLGRRGF LQTLNATLGC VLHRLADLEQ RLPKAQDLER SGLNIEDLEK LQMARPNILG LRNNIYCMAQ LLDNSDTAEP TKAGRGASQP PTPTPASDAF QRKLEGCRFL HGYHRFMHSV GRVFSKWGES PNRSRR

特异性

Ala26-Arg221

过滤

0.22 μm filtered

内毒素水平

< 0.01 EU/μg of the protein by LAL method.

Biological Activity Comment

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effect is typically 0.8-3.2 ng/mL, corresponding to a specific activity of 3.12x10⁵-1.25x10⁶units/mg.
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Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag)
OSM 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Oncostatin M (OSM) (AA 25-206) protein (His tag)
OSM 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag,Biotin)
OSM 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Oncostatin M (OSM) (AA 26-221) protein (His tag)
OSM 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

Oncostatin M (OSM) (AA 26-239) protein (His tag)
OSM 宿主: 大鼠宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

Oncostatin M (OSM) (AA 1-252) protein (GST tag)
OSM 宿主: 人宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

Oncostatin M (OSM) (AA 26-234) protein (His tag)
OSM 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS

Oncostatin M (OSM) protein (His tag)
OSM 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.

Oncostatin M (OSM) (AA 26-252) protein
OSM 宿主: 人宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.

Oncostatin M (OSM) protein
OSM 宿主: 人 Recombinant BCA

限制

仅限研究用
状态

Lyophilized

溶解方式

Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

缓冲液

Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, 5 % glycerol, pH 7.4.

储存条件

-20 °C,-80 °C

储存方法

Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
抗原

Oncostatin M (OSM)

别名

Oncostatin-M/OSM

背景

Description: This protein is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family. The preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells.
Name: OSM, oncostatin-M

基因ID

5008

UniProt

P13725

途径

JAK/STAT Signaling, Negative Regulation of Hormone Secretion

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