Oncostatin M Protein (OSM) (His tag)
Quick Overview for Oncostatin M Protein (OSM) (His tag) (ABIN7536079)
抗原
See all Oncostatin M (OSM) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Oncostatin M protein is labelled with His tag.
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原理
- Recombinant Mouse Oncostatin-M/OSM Protein
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序列
- MQTRLLRTLL SLTLSLLILS MALANRGCSN SSSQLLSQLQ NQANLTGNTE SLLEPYIRLQ NLNTPDLRAA CTQHSVAFPS EDTLRQLSKP HFLSTVYTTL DRVLYQLDAL RQKFLKTPAF PKLDSARHNI LGIRNNVFCM ARLLNHSLEI PEPTQTDSGA SRSTTTPDVF NTKIGSCGFL WGYHRFMGSV GRVFREWDDG STRSRR
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特异性
- Met 1-Arg 206
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过滤
- 0.22 μm filtered
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内毒素水平
- <0.1EU/μg
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- Oncostatin M (OSM)
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别名
- Oncostatin-M/OSM
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背景
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Description: OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Name: OncoM,OSM
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基因ID
- 18413
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UniProt
- P53347
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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