IL12B 蛋白
Quick Overview for IL12B 蛋白 (ABIN7536177)
抗原
See all IL12B 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Active Recombinant Mouse IL-12B Protein
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序列
- MWELEKDVYV VEVDWTPDAP GETVNLTCDT PEEDDITWTS DQRHGVIGSG KTLTITVKEF LDAGQYTCHK GGETLSHSHL LLHKKENGIW STEILKNFKN KTFLKCEAPN YSGRFTCSWL VQRNMDLKFN IKSSSSSPDS RAVTCGMASL SAEKVTLDQR DYEKYSVSCQ EDVTCPTAEE TLPIELALEA RQQNKYENYS TSFFIRDIIK PDPPKNLQMK PLKNSQVEVS WEYPDSWSTP HSYFSLKFFV RIQRKKEKMK ETEEGCNQKG AFLVEKTSTE VQCKGGNVCV QAQDRYYNSS CSKWACVPCR VRS
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特异性
- Met23-Ser335
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过滤
- 0.22 μm filtered
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内毒素水平
- <0.1EU/μg
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized Mouse IL12B at 10 μg/mL (100 μL/well) can bind Human IL12RB1 with a linear range of 0.02-51 ng/mL.
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Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)
IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 beta (IL12B) protein (His tag)IL12B 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
Interleukin 12 beta (IL12B) (AA 229-328) protein (GST tag)IL12B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 12 beta (IL12B) (AA 23-328), (full length) protein (GST tag)IL12B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Interleukin 12 beta (IL12B) (AA 23-328) (Active) protein (His tag)IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 12 beta (IL12B) (AA 23-328) protein (Fc Tag)IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Interleukin 12 beta (IL12B) (AA 23-327), (full length) protein (His tag)IL12B 宿主: 绵羊 宿主: 酵母菌 Recombinant > 90 % ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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浓度
- 1.7 mg/mL
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- IL12B (Interleukin 12 beta (IL12B))
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别名
- IL-12B
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背景
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Description: Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities.IL12B/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
Name: p40, Il-12b, Il12p40, Il-12p40,IL12B
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基因ID
- 16160
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UniProt
- P43432
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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