CD276 Protein (CD276) (Fc Tag)
Quick Overview for CD276 Protein (CD276) (Fc Tag) (ABIN7536266)
抗原
See all CD276 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This CD276 protein is labelled with Fc Tag.
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原理
- Active Recombinant Mouse CD276 Protein
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序列
- VEVQVSEDPV VALVDTDATL RCSFSPEPGF SLAQLNLIWQ LTDTKQLVHS FTEGRDQGSA YSNRTALFPD LLVQGNASLR LQRVRVTDEG SYTCFVSIQD FDSAAVSLQV AAPYSKPSMT LEPNKDLRPG NMVTITCSSY QGYPEAEVFW KDGQGVPLTG NVTTSQMANE RGLFDVHSVL RVVLGANGTY SCLVRNPVLQ QDAHGSVTIT GQPLTF
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特异性
- Val 29 - Phe 244
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过滤
- 0.22 μm filtered
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内毒素水平
- <1EU/μg
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Biological Activity Comment
- Measured by its binding ability in a functional ELISA.Immobilized Mouse CD276 at 2 μg/mL (100 μL/well) can bind CD276 Rabbit pAb with a linear range of 1-77.4 ng/mL.
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CD276 (CD276) (AA 29-245) protein (His tag)
CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD276 (CD276) (AA 27-461) protein (Fc Tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-245) protein (His-Avi Tag,Biotin)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-245) protein (mFc-His Tag)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD276 (CD276) (AA 29-248) protein (His tag)CD276 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD276 (CD276) (AA 29-244) protein (Fc Tag)CD276 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD276 (CD276) (AA 28-140) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 237-461) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 28-238) protein (His-DYKDDDDK-Strep II Tag)CD276 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD276 (CD276) (AA 29-245) protein (Fc Tag,AVI tag,Biotin)CD276 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- CD276
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别名
- CD276
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背景
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Description: B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity.
Name: B7h3, B7RP-2, 6030411F23Rik,CD276
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基因ID
- 102657
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UniProt
- Q8VE98
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途径
- Cancer Immune Checkpoints
抗原
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