Adrenomedullin Protein (ADM) (AA 21-185) (His tag)
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- 抗原 See all Adrenomedullin (ADM) 蛋白
- Adrenomedullin (ADM)
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-185
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Adrenomedullin protein is labelled with His tag.
- 序列
- Thr 21-Leu 185
- 产品特性
- A DNA sequence encoding the Rat Adrenomedullin/ADM protein (P43145) (Thr 21-Leu 185) was expressed with a N-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ADM 蛋白
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Adrenomedullin (ADM) (AA 1-185) protein (GST tag)
ADM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- Adrenomedullin (ADM)
- 别名
- Adrenomedullin (ADM 产品)
- 物质类
- Hormone
- 背景
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Abbreviation: Adrenomedullin,ADM
Target Synonym: ADM precursor,Adrenomedullin,PAMP,Preproadrenomedullin,ProAM N terminal 20 peptide,ProAM N20
Background: Adrenomedullin (ADM, also AM) is a secreted, monomeric, 6 kDa member of the Adrenomedullin family of molecules. It is widely expressed, being found in smooth muscle cells, endothelium, adrenal medulla chromaffin cells, fibroblasts and keratinocytes. ADM has multiple functions, including vasodilation, the maintenance of vascular integrity, and the suppression of inflammatory mediator secretion. The ADM preproprecursor is 185 amino acids (aa) in length. It contains a 21 aa signal sequence, a processed 20 aa peptide termed PAMP (aa 22-41), an N-terminal propeptide (aa 45-91), the ADM precursor (amidation is required for maturation) (aa 94 143), and a C-terminal propeptide (aa 150-185). The ADM precursor with a terminal Gly147 circulates naturally with bioactive, mature amidated ADM (aa 94 143).
- 分子量
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Calculated MW: 18.04 kDa
Observed MW: 25 kDa
- UniProt
- P43145
- 途径
- Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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