RAB11A Protein (AA 2-212) (His tag)
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- 抗原 See all RAB11A 蛋白
- RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-212
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This RAB11A protein is labelled with His tag.
- 序列
- Gly 2-Cys 212
- 产品特性
- A DNA sequence encoding the Human RAB11A protein (P62491) (Gly 2-Cys 212) was expressed with a N-His&C-His tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product RAB11A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))
- 别名
- RAB11A (RAB11A 产品)
- 背景
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Abbreviation: RAB11A
Target Synonym: Ras-related protein Rab-11A,RAB11A,Rab-11
Background: Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes.
- 分子量
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Calculated MW: 23.1 kDa
Observed MW: 30 kDa
- UniProt
- P62491
- 途径
- Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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