GSK3 alpha Protein (AA 97-448)
Quick Overview for GSK3 alpha Protein (AA 97-448) (ABIN7505000)
抗原
See all GSK3 alpha (GSK3a) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 97-448
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序列
- Ser97-Pro448
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产品特性
- A DNA sequence encoding the Human GSK3α Protein (P49840)(97-448)was expressed with a polyhistidine tag at the N-terminus.
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Glycogen Synthase Kinase 3 alpha (GSK3a) protein (Myc-DYKDDDDK Tag)
GSK3a 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Glycogen Synthase Kinase 3 alpha (GSK3a) proteinGSK3a 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
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别名
- GSK3alpha
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背景
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Abbreviation: GSK3α
Target Synonym: Glycogen synthase kinase-3 alpha,GSK-3 alpha,Serine/threonine-protein kinase GSK3A,GSK3A
Background: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1.
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分子量
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Calculated MW: 39.4 kDa
Observed MW: 39 kDa
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UniProt
- P49840
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途径
- PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
抗原
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