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CCL5 Protein (AA 24-91)

This Recombinant CCL5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7504996
发货至: 中国

Quick Overview for CCL5 Protein (AA 24-91) (ABIN7504996)

抗原

See all CCL5 蛋白
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 24-91

    序列

    Ser24-Ser91

    产品特性

    A DNA sequence encoding the Human CCL5/RANTES Protein(P13501)(Ser24-Ser91)was expressed with N-SUMO&C-His tag.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    别名

    CCL5

    背景

    Abbreviation: CCL5,RANTES

    Target Synonym: C-C motif chemokine 5,EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,T-cell-specific protein RANTES,D17S136E,SCYA5

    Background: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils

    分子量

    Calculated MW: 22.3 kDa

    Observed MW: 25 kDa

    UniProt

    P13501

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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