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IL-4 Protein (AA 25-153)

This Recombinant IL-4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7504977
发货至: 中国

Quick Overview for IL-4 Protein (AA 25-153) (ABIN7504977)

抗原

See all IL-4 (IL4) 蛋白
IL-4 (IL4) (Interleukin 4 (IL4))

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 25-153

    序列

    His25-Ser153

    产品特性

    A DNA sequence encoding the Human IL4 protein (P05112) (His25-Ser153) was expressed with a polyhistidine tag at the N-terminus.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    IL-4 (IL4) (Interleukin 4 (IL4))

    别名

    IL-4

    背景

    Abbreviation: IL-4

    Target Synonym: Interleukin-4,IL4,B-cell stimulatory factor 1,BSF-1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra

    Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.

    分子量

    Calculated MW: 15 kDa

    Observed MW: 16 kDa

    UniProt

    P05112

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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