LI Cadherin Protein (Fc Tag)
Quick Overview for LI Cadherin Protein (Fc Tag) (ABIN7489104)
抗原
See all LI Cadherin 蛋白蛋白类型
宿主
资源
纯度
质量等级
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标记
- This LI Cadherin protein is labelled with Fc Tag.
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原理
- Mouse Cadherin-17 / CDH17 Protein, Fc Tag (MALS verified)
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序列
- Phe 26 - Met 786
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产品特性
- Mouse Cadherin-17 Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Phe 26 - Met 786 (Accession # Q9R100-1).
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内毒素水平
- 1.0 EU per μg
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说明
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This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 110.8 kDa. The protein migrates as 50 kDa and 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 20 mM Tris, 150 mM NaCl, pH 8.0
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储存条件
- -20 °C
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储存方法
- -20°C
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- LI Cadherin
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别名
- Cadherin-17
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背景
- Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
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分子量
- 110.8 kDa
抗原
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