TNFSF15 蛋白
Quick Overview for TNFSF15 蛋白 (ABIN7488820)
抗原
See all TNFSF15 蛋白蛋白类型
宿主
资源
纯度
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原理
- Human TL1A / TNFSF15 Protein, His Tag
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序列
- Met 1 - Leu 192
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产品特性
- Human TL1A Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Leu 192 (Accession # O95150-2).
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内毒素水平
- 1.0 EU per μg
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 136,947.45 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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说明
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This protein carries a polyhistidine tag at the N-terminus. () The protein has a calculated MW of 23.7 kDa. The protein migrates as 30 kDa and 31-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
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别名
- TL1A
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背景
- TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.
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分子量
- 23.7 kDa
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途径
- Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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