SLC7A11 & SLC3A2 protein-VLP
宿主: 人
宿主: HEK-293 Cells
VLP
-
- 抗原
- SLC7A11 & SLC3A2
- 蛋白类型
- VLP
- 宿主
- 人
- 资源
- HEK-293 Cells
- 原理
- Human SLC7A11&SLC3A2 Full Length Heterodimer Protein (VLP)
- 序列
- Val 2 - Leu 501 (SLC7A11) & Glu 2- Ala 630 (SLC3A2)
- 产品特性
- Human SLC7A11&SLC3A2 Full Length Heterodimer Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Val 2 - Leu 501 (SLC7A11) & Glu 2- Ala 630 (SLC3A2) (Accession # Q9UPY5 (SLC7A11) & P08195 (SLC3A2).
- 内毒素水平
- 1.0 EU per μg
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS, Arginine, pH 7.4
- 储存条件
- -80 °C
- 储存方法
- -70°C
-
- 抗原
- SLC7A11 & SLC3A2
- 背景
- Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring specialised transport systems for its import into the cell. System xc- is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc- is frequently upregulated, making it an attractive target for anticancer therapies.
-
You are here:
