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Claudin 9 Protein-VLP (CLDN9)

This VLP Claudin 9 protein is expressed in HEK-293 Cells.
产品编号 ABIN7488753
发货至: 中国

Quick Overview for Claudin 9 Protein-VLP (CLDN9) (ABIN7488753)

抗原

See all Claudin 9 (CLDN9) 蛋白
Claudin 9 (CLDN9)

蛋白类型

VLP

宿主

  • 7
  • 2

资源

  • 5
  • 2
  • 1
  • 1
HEK-293 Cells
  • 原理

    Human Claudin-9 / CLDN9 Full Length Protein (VLP)

    序列

    Met 1 -Val 217

    产品特性

    Human Claudin-9 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Met 1 -Val 217 (Accession # O95484-1).

    内毒素水平

    1.0 EU per μg
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 136,947.45 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, Arginine, pH 7.4

    储存条件

    -80 °C

    储存方法

    -70°C
  • 抗原

    Claudin 9 (CLDN9)

    别名

    Claudin-9

    背景

    Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus, it enables HCV entry into target cells just as efficiently as CLDN1.

    途径

    Cell-Cell Junction Organization, Hepatitis C
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