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CD5 Protein (CD5) (Biotin,His-Avi Tag)

This Recombinant CD5 protein is expressed in HEK-293 Cells.
产品编号 ABIN7489028
发货至: 中国
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Quick Overview for CD5 Protein (CD5) (Biotin,His-Avi Tag) (ABIN7489028)

抗原

See all CD5 蛋白
CD5

蛋白类型

Recombinant

宿主

  • 20
  • 5
  • 4
  • 2
  • 1
小鼠

资源

  • 18
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

90 %

质量等级

MALS verified
  • 标记

    This CD5 protein is labelled with Biotin,His-Avi Tag.

    原理

    Biotinylated Mouse CD5 Protein, His,Avitag™ (MALS verified)

    序列

    Gln 24 - Asn 370

    产品特性

    Biotinylated Mouse CD5 Protein, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Asn 370 (Accession # P13379).

    内毒素水平

    1.0 EU per μg
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  • 说明

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 41.4 kDa. The protein migrates as 53-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    CD5

    别名

    CD5

    背景

    T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.

    分子量

    41.4 kDa
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