CD33 Protein (CD33) (APC,His tag)
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Quick Overview for CD33 Protein (CD33) (APC,His tag) (ABIN7482336)
抗原
See all CD33 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD33 protein is labelled with APC,His tag.
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原理
- APC-Labeled Human Siglec-3 / CD33 Protein, His TagStar Staining
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序列
- Asp 18 - His 259
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产品特性
- APC-Labeled Human Siglec-3 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 18 - His 259 (Accession # AAH28152.1).
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内毒素水平
- 1.0 EU per μg
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CD33 (CD33) (AA 18-259) protein (His-Avi Tag)
CD33 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
CD33 (CD33) (AA 18-259) protein (Fc Tag)CD33 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD33 (CD33) (AA 18-259) protein (His-Avi Tag,Biotin)CD33 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
CD33 (CD33) (AA 17-248) protein (His tag)CD33 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD33 (CD33) (AA 18-259) protein (Fc-His Tag)CD33 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD33 (CD33) protein (His tag)CD33 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
CD33 (CD33) (AA 1-364) protein (GST tag)CD33 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD33 (CD33) (AA 18-259) (Active) protein (His-Fc tag)CD33 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. ELISA, WB, SDS, AcA, Imm Active
CD33 (CD33) (AA 18-259) protein (His tag)CD33 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
CD33 (CD33) (AA 140-259) protein (Fc Tag)CD33 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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说明
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This protein carries a polyhistidine tag at the C-terminus. (APC ,10xHis) The protein has a calculated MW of 41.5 kDa.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, 0.2 % BSA, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C, avoid light
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- CD33
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别名
- Siglec-3
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背景
- Myeloid cell surface antigen CD33 is also known as SIGLEC3, Siglecs (sialic acid binding Ig-like lectins) and GP67, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Human CD33 / Siglec-3 cD encodes a 364 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N--terminal Ig--like V--type domain, one Ig--like C2--type domains, a transmembrane region and a cytoplasmic tail. CD33 / Siglec-3 usually considered myeloid-specific, but it can also be found on some lymphoid cells. In the immune response, CD33 / Siglec-3 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 / Siglec-3 induces apoptosis in acute myeloid leukemia.
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分子量
- 41.5 kDa
抗原
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