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MRGPRX2 Protein (AA 1-33) (Fc Tag)

This Recombinant MRGPRX2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7491443
发货至: 中国

Quick Overview for MRGPRX2 Protein (AA 1-33) (Fc Tag) (ABIN7491443)

抗原

See all MRGPRX2 蛋白
MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

蛋白类型

Recombinant

宿主

  • 6
  • 2

资源

  • 4
  • 2
  • 2
HEK-293 Cells

纯度

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 1-33

    标记

    This MRGPRX2 protein is labelled with Fc Tag.

    原理

    Recombinant Human MRGPRX2 Protein with C-terminal human Fc tag

    特异性

    MRGPRX2 (Met1-Pro33) hFc (Glu99-Ala330)

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 152,621.24 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

    别名

    MRGPRX2

    背景

    Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.[UniProtKB/Swiss-Prot Function]

    分子量

    predicted molecular mass of 29.6 kDa after removal of the signal peptide. The apparent molecular mass of MRGPRX2-hFc is 35-55 kDa due to glycosylation.

    UniProt

    Q96LB1
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