MRGPRX2 Protein (AA 1-33) (Fc Tag)
Quick Overview for MRGPRX2 Protein (AA 1-33) (Fc Tag) (ABIN7491443)
抗原
See all MRGPRX2 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 1-33
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标记
- This MRGPRX2 protein is labelled with Fc Tag.
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原理
- Recombinant Human MRGPRX2 Protein with C-terminal human Fc tag
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特异性
- MRGPRX2 (Met1-Pro33) hFc (Glu99-Ala330)
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 152,621.24 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
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别名
- MRGPRX2
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背景
- Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.[UniProtKB/Swiss-Prot Function]
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分子量
- predicted molecular mass of 29.6 kDa after removal of the signal peptide. The apparent molecular mass of MRGPRX2-hFc is 35-55 kDa due to glycosylation.
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UniProt
- Q96LB1
抗原
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