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CCL5 蛋白

This Recombinant CCL5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7455688
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCL5 蛋白 (ABIN7455688)

抗原

See all CCL5 蛋白
CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

纯度

Greater than 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human C-C Motif Chemokine 5 is produced by our E.coli expression system and the target gene encoding Ser24-Ser91 is expressed.

    产品特性

    Extracellular Domain Protein

    纯化方法

    Affinity purification
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  • 应用备注

    Extracellular Domain Proteins (ECD) can be used as:
    • Immunogens for antibody drug development
    • Reagents used for CAR-T positive cell monitoring
    • Reagents for antibody screening and functional testing
    • Reagents for antibody affinity measurement

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

    别名

    CCL5

    背景

    C-C Motif Chemokine 5,EoCP,Eosinophil Chemotactic Cytokine,SIS-Delta,Small-Inducible Cytokine A5,T Cell-Specific Protein P228,TCP228,T-Cell-Specific Protein RANTES,CCL5,D17S136E,SCYA5
    Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.

    分子量

    7.8 KDa

    UniProt

    P13501

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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