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Quick Overview for MYDGF Protein (His tag) (ABIN7455641)
抗原
See all MYDGF (D17Wsu104e) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This MYDGF protein is labelled with His tag.
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原理
- Recombinant Human Myeloid-derived Growth Factor is produced by our E.coli expression system and the target gene encoding Ser33-Leu173 is expressed with a 6His tag at the N-terminus.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Affinity purification
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DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e) (AA 32-173) protein (His tag)
D17Wsu104e 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e) (AA 33-173) protein (His tag)D17Wsu104e 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e) (AA 25-166) protein (His tag)D17Wsu104e 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
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别名
- MYDGF
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背景
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UPF0556 protein C19orf10,stromal cell-derived growth factor SF20,C19orf10,Myeloid-derived growth factor,MYDGF
Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair. -
分子量
- 18 KDa
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UniProt
- Q969H8
抗原
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