Oncostatin M Protein (OSM) (His tag)
Quick Overview for Oncostatin M Protein (OSM) (His tag) (ABIN7455625)
抗原
See all Oncostatin M (OSM) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Oncostatin M protein is labelled with His tag.
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原理
- Recombinant Human Oncostatin M is produced by our E.coli expression system and the target gene encoding Ala26-Arg221 is expressed with a 6His tag at the N-terminus.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Affinity purification
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Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag)
OSM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 25-206) protein (His tag)OSM 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag,Biotin)OSM 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 26-221) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Oncostatin M (OSM) (AA 26-239) protein (His tag)OSM 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Oncostatin M (OSM) (AA 1-252) protein (GST tag)OSM 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Oncostatin M (OSM) (AA 26-234) protein (His tag)OSM 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Oncostatin M (OSM) (AA 26-252) proteinOSM 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mMTris-HCl, 1 mM EDTA, 200 mM NaCl, pH 7.5.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- Oncostatin M (OSM)
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别名
- OSM
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背景
- Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological activities through specific cell surface receptors. The low affinity LIF receptor that shares the similarity of containing protein gp130 has now been identified to be a component of a high- affinity OSM receptor that will transduce OSM signals. OSM has also been shown to play a role in both pro and anti-inflammatory actions. OSM may also be involved in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development.
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分子量
- 24.44 KDa
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UniProt
- P13725
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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