CD28 Protein (CD28) (His tag)
Quick Overview for CD28 Protein (CD28) (His tag) (ABIN7447918)
抗原
See all CD28 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD28 protein is labelled with His tag.
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原理
- Rat CD28 Protein, His Tag (BLI verified)
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序列
- Asn 20 - Leu 150
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产品特性
- Rat CD28, His Tag is expressed from human 293 cells (HEK293). It contains AA Asn 20 - Leu 150 (Accession # P31042-1).
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内毒素水平
- 1.0 EU per μg
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说明
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.9 kDa. The protein migrates as 30-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- CD28
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别名
- CD28
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背景
- Synonyms:CD28,Tp44,Description:T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
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分子量
- 16.9 kDa
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NCBI登录号
- NP_037253
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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