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CD4 Protein (CD4) (Biotin,His-Avi Tag)

This Recombinant CD4 protein is expressed in HEK-293 Cells.
产品编号 ABIN7316799
发货至: 中国

Quick Overview for CD4 Protein (CD4) (Biotin,His-Avi Tag) (ABIN7316799)

抗原

See all CD4 蛋白
CD4

蛋白类型

Recombinant

宿主

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猕猴

资源

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HEK-293 Cells

纯度

95,00 %

质量等级

MALS verified
  • 标记

    This CD4 protein is labelled with Biotin,His-Avi Tag.

    原理

    Biotinylated Rhesus macaque CD4 Protein, His,Avitag™ (MALS verified)

    序列

    Lys 26 - Trp 390

    产品特性

    Biotinylated Rhesus macaque CD4,His,Avitag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8-1).

    内毒素水平

    1.0 EU per μg
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  • 说明

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.0 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    CD4

    别名

    CD4

    背景

    Synonyms:CD4,CD4mut,LEU3,Description:T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

    分子量

    44.0 kDa

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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