CD4 Protein (CD4) (Biotin,His-Avi Tag)
Quick Overview for CD4 Protein (CD4) (Biotin,His-Avi Tag) (ABIN7316799)
抗原
See all CD4 蛋白蛋白类型
宿主
资源
纯度
质量等级
-
-
标记
- This CD4 protein is labelled with Biotin,His-Avi Tag.
-
原理
- Biotinylated Rhesus macaque CD4 Protein, His,Avitag™ (MALS verified)
-
序列
- Lys 26 - Trp 390
-
产品特性
- Biotinylated Rhesus macaque CD4,His,Avitag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8-1).
-
内毒素水平
- 1.0 EU per μg
-
-
-
-
说明
-
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.0 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- PBS, pH 7.4
-
储存条件
- -20 °C
-
储存方法
- -20°C
-
-
- CD4
-
别名
- CD4
-
背景
- Synonyms:CD4,CD4mut,LEU3,Description:T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
-
分子量
- 44.0 kDa
-
途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
-