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LI Cadherin Protein (Biotin,His-Avi Tag)

This Recombinant LI Cadherin protein is expressed in HEK-293 Cells.
产品编号 ABIN7316790
发货至: 中国
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Quick Overview for LI Cadherin Protein (Biotin,His-Avi Tag) (ABIN7316790)

抗原

See all LI Cadherin 蛋白
LI Cadherin

蛋白类型

Recombinant

宿主

  • 29
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资源

  • 27
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HEK-293 Cells

纯度

95,00 %

质量等级

MALS verified
  • 标记

    This LI Cadherin protein is labelled with Biotin,His-Avi Tag.

    原理

    Biotinylated Human Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)

    序列

    Gln 23 - Met 787

    产品特性

    Biotinylated Human Cadherin-17, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).

    内毒素水平

    1.0 EU per μg
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  • 说明

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 88.6 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    20 mM Tris, 150 mM NaCl, pH 8.0

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    LI Cadherin

    别名

    Cadherin-17

    背景

    Synonyms:Cadherin-17,CDH17,HPT-1, LI-cadherin,Description:Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

    分子量

    88.6 kDa
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