SNCA Protein (E46K)
Quick Overview for SNCA Protein (E46K) (ABIN7316762)
抗原
See all SNCA 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- E46K
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原理
- Human Alpha-Synuclein (E46K) Protein, Tag Free (MALS verified)
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序列
- Met 1 - Ala 140
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产品特性
- Human Alpha-Synuclein (E46K), Tag Free is expressed from E.coli cells. It contains AA Met 1 - Ala 140 (Accession # P37840-1 (E46K).
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内毒素水平
- 1.0 EU per μg
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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说明
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This protein carries no "tag". The protein has a calculated MW of 14.5 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 50 mM HEPES, 100 mM NaCl, pH 8.0
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储存条件
- -80 °C
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储存方法
- -70°C
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- SNCA (Synuclein, alpha (SNCA))
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别名
- Alpha-Synuclein
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背景
- Synonyms:N/A,Description:Alpha-synuclein is a neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. It acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DJC5. Abnormalities in alpha-synuclein are implicated in the pathogenesis of Parkinson's disease (PD). Alpha-synuclein is present in Lewy-bodies, the neuropathological hallmark of PD, and the protein and its aggregation have been widely linked to neurotoxic pathways that ultimately lead to neurodegeneration.
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分子量
- 14.5 kDa
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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