PVRIG Protein (AA 41-171) (Fc Tag)
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- 抗原 See all PVRIG 蛋白
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 41-171
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This PVRIG protein is labelled with Fc Tag.
- 原理
- Cynomolgus PVRIG Protein
- 序列
- Thr41-Asp171
- 产品特性
- Recombinant Cynomolgus PVRIG Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr41-Asp171.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus PVRIG, hFc Tag at 0.1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-PVRIG Antibody, hFc Tag with the EC50 of 5.4ng/ml determined by ELISA. The affinity constant of 0.23 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product PVRIG 蛋白
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Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (mFc Tag)
PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) protein (His tag)PVRIG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) protein (Fc Tag)PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) protein (Fc-Avi Tag)PVRIG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (Active) protein (mFc Tag)PVRIG 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) protein (Fc-Avi Tag,Biotin)PVRIG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (Fc Tag,AVI tag,Biotin)PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 38-326) protein (GST tag)PVRIG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 1-326) protein (Strep Tag)Crystallography grade PVRIG 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
- 别名
- PVRIG (PVRIG 产品)
- 别名
- C7orf15 Protein, PVR related immunoglobulin domain containing Protein, PVRIG Protein
- 背景
- PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.PVRIG is a cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
- 分子量
- 40.3 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
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