Our Local Distributor
北京 101111
Quick Overview for PVRIG Protein (mFc Tag) (ABIN7319903)
抗原
See all PVRIG 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
标记
- This PVRIG protein is labelled with mFc Tag.
-
原理
- Recombinant Human PVRIG (C-mFc)
-
序列
- Thr41-Asp171
-
产品特性
- Recombinant Human Transmembrane Protein PVRIG is produced by our Mammalian expression system and the target gene encoding Thr41-Asp171 is expressed with a mFc tag at the C-terminus.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
Biological Activity Comment
- 1.Immobilized Human PVRIG-mFc(Cat#C08Y) at 10μg/ml (100 μl/well) can bind Human Nectin-2-His(Cat#C440).The ED50 of Human Nectin-2-His(Cat#C440) is 3.72 ug/ml. 2.Immobilized Human PVRIG-mFc(Cat#C08Y) at 10μg/ml (100 μl/well) can bind Biotinylated Human Nectin-2-His-Avi(Cat#CY73). The ED50 of Biotinylated Human Nectin-2-His-Avi(Cat#CY73) is 0.42 ug/ml.
-
-
想要此Protein的其他选项吗？
!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 150,642.20 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 145,985.55 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (hFc Tag)
PVRIG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 1-326) protein (His tag)custom-made PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) (Active) protein (hFc-Avi Tag)PVRIG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 35-165) (Active) protein (hFc-Avi Tag,Biotin)PVRIG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (DYKDDDDK Tag)PVRIG 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc ELISA, Imm, cryo-EM, PhD, SPR
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 41-171) (Active) protein (His tag)PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) protein (His tag)PVRIG 宿主: Cynomolgus 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 38-326) protein (GST tag)PVRIG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG) (AA 99-330) protein (Fc Tag)PVRIG 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))
-
别名
- PVRIG
-
背景
-
Background: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The extracellular domain sequence of human and mouse PVRIG have approximately 65 % similarity. PVRIG functions as a cell surface receptor for Nectin-2/CD112, a cell surface protein that is widely expressed on antigen-presenting cells and tumor cells. Disrupting the PVRIG/Nectin-2 interaction enhances human T cell response, suggesting PVRIG is a novel checkpoint for human T cells. PVRIG may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Synonym: C7orf15, CD112R, PVRIG, transmembrane protein PVRIG, C7orf15MGC138295, MGC104322, MGC138297, MGC2463
-
分子量
- 40.1 kDa
-
UniProt
- Q6DKI7
抗原
-
