CD45 Protein (AA 26-416) (His-Avi Tag,Biotin)
Quick Overview for CD45 Protein (AA 26-416) (His-Avi Tag,Biotin) (ABIN7275501)
抗原
See all CD45 (PTPRC) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 26-416
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标记
- This CD45 protein is labelled with His-Avi Tag,Biotin.
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原理
- Biotinylated Human CD45/PTPRC Protein
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序列
- Gln26--Lys416
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产品特性
- Recombinant Biotinylated Human CD45/PTPRC Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln26--Lys416.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 26-416) protein (His-Avi Tag)
PTPRC 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 26-577) protein (His tag)PTPRC 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1031-1251) protein (His tag)PTPRC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 915-1306) protein (His tag)PTPRC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 390-570) protein (GST tag)PTPRC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 1207-1304) protein (GST tag)PTPRC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 26-566) protein (His tag)PTPRC 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (Active) protein (Fc Tag)PTPRC 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (Active) protein (GST tag,His tag)PTPRC 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (Active) proteinPTPRC 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
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别名
- CD45
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背景
- PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
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分子量
- 47.3 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
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UniProt
- P08575-4
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
抗原
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