Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag)
Quick Overview for Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag) (ABIN7275496)
抗原
See all Microseminoprotein, Prostate Associated (MSMP) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 37-139
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标记
- Fc Tag
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原理
- Mouse PSMP Protein
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序列
- Lys37-Ser139
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产品特性
- Recombinant Mouse PSMP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Microseminoprotein, Prostate Associated (MSMP) (AA 37-139) protein (Fc Tag)
MSMP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Microseminoprotein, Prostate Associated (MSMP) (AA 36-139) protein (Fc Tag)MSMP 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Microseminoprotein, Prostate Associated (MSMP) protein (Myc-DYKDDDDK Tag)MSMP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- Microseminoprotein, Prostate Associated (MSMP)
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别名
- PSMP
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背景
- PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.
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分子量
- 37.9 kDa. Due to glycosylation, the protein migrates to 48-51 kDa based on Tris-Bis PAGE result.
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UniProt
- B1AWI6
抗原
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