Klotho beta Protein (KLB) (AA 53-994) (His tag)
Quick Overview for Klotho beta Protein (KLB) (AA 53-994) (His tag) (ABIN7275093)
抗原
See all Klotho beta (KLB) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 53-994
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标记
- This Klotho beta protein is labelled with His tag.
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原理
- Mouse Beta Klotho Protein
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序列
- Phe53-Pro994
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产品特性
- Recombinant Mouse Beta Klotho Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe53-Pro994.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Klotho beta (KLB) (AA 30-983) protein (His tag)
KLB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Klotho beta (KLB) (AA 1-1043) protein (His tag)custom-made KLB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Klotho beta (KLB) (AA 1-1044) protein (His tag)custom-made KLB 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
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储存条件
- -80 °C
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储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- Klotho beta (KLB)
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别名
- Beta Klotho
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背景
- Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites.
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分子量
- 109.91 kDa. Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result.
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UniProt
- Q99N32-1
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
抗原
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