IL-17A/F Protein (AA 26-158) (His-Avi Tag)
Quick Overview for IL-17A/F Protein (AA 26-158) (His-Avi Tag) (ABIN7274968)
抗原
See all IL-17A/F 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 26-158
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标记
- This IL-17A/F protein is labelled with His-Avi Tag.
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原理
- Mouse IL-17A&F Protein
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序列
- Ala26-Ala158(IL-17A) & Arg29-Ala161(IL-17F)
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特异性
- Uni-Prot: Q62386 (IL-17A), Q7TNI7-1 (IL-17F)
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产品特性
- Recombinant Mouse IL-17A&F Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Ala158(IL-17A)&Arg29-Ala161(IL-17F).
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Mouse IL-17A&F, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 19.8ng/ml determined by ELISA. See testing image for detail.
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Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag)
IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 26-158) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His-Avi Tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) proteinIL-17A/F 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
Interleukin-17 A/F Heterodimer (IL-17A/F) (AA 24-155) protein (His tag,AVI tag,Biotin)IL-17A/F 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
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别名
- IL-17A&F
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背景
- Interleukin-17A (IL-17A), also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
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分子量
- 17.9 kDa(IL-17A)&14.9 kDa(IL-17F). Due to glycosylation, the protein migrates to 22-25 kDa&27-30 kDa based on Tris-Bis PAGE result.
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UniProt
- Q62386
抗原
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