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IL-7 Protein (AA 26-177)

This Recombinant IL-7 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7274963
发货至: 中国

Quick Overview for IL-7 Protein (AA 26-177) (ABIN7274963)

抗原

See all IL-7 (IL7) 蛋白
IL-7 (IL7) (Interleukin 7 (IL7))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 26-177

    原理

    Human IL-7 Protein

    序列

    Asp26-His177

    产品特性

    Recombinant Human IL-7 Protein is expressed from E.coli without tag.It contains Asp26-His177.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 0.1 EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested). The affinity constant of 7.15 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IL-7 (IL7) (Interleukin 7 (IL7))

    别名

    IL-7

    背景

    Interleukin-7 (IL7) plays a nonredundant role in T cell survival and homeostasis, which is illustrated in the severe T cell lymphopenia of IL7-deficient mice, or demonstrated in animals or humans that lack expression of either the IL7Rα or γ c chain, the two subunits that constitute the functional IL7 receptor.

    分子量

    17.5 kDa same as Tris-Bis PAGE result.

    UniProt

    P13232

    途径

    JAK/STAT Signaling
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