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IL-15 Protein (AA 49-162)

This Recombinant IL-15 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7274953
发货至: 中国

Quick Overview for IL-15 Protein (AA 49-162) (ABIN7274953)

抗原

See all IL-15 (IL15) 蛋白
IL-15 (IL15) (Interleukin 15 (IL15))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

>95 % as determined by Tris-Bis PAGE, > 95 % as determined by SEC-HPLC
  • 产品特性

    AA 49-162

    原理

    Human IL-15 Protein

    序列

    Asn49-Ser162

    产品特性

    Recombinant Human IL-15 Protein is expressed from E.coli without tag., It contains Asn49-Ser162.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 0.05 EU per μg by the LAL method.

    Biological Activity Comment

    Measured in a cell proliferation assay using CTLL­2 cells. The ED50 for this effect is 0.1 ­ 0.3 ng/mL. The specific activity of recombinant human IL­15 is > 1 x 10^7 units/mg, which is calibrated against the human IL­15 reference standard (NIBSC code: 95/554). Test result was comparable to standard batch.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4) / 20 mM Tris, 150 mM NACI ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IL-15 (IL15) (Interleukin 15 (IL15))

    别名

    IL-15

    背景

    Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseases. IL-15 is a cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA.

    分子量

    12.8 kDa same as Tris-Bis PAGE result.

    UniProt

    P40933

    途径

    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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