IL-2 Protein (AA 21-153)
-
- 抗原 See all IL-2 (IL2) 蛋白
- IL-2 (IL2) (Interleukin 2 (IL2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-153
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 原理
- Human IL-2 Protein
- 序列
- Ala21-Thr153
- 产品特性
- Recombinant Human IL-2 Protein is expressed from E.coli without tag.It contains Ala21-Thr153.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 15.2nM as determined in SPR assay (Biacore T200). See testing image for detail.
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 100 mM Acetic Acid.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in 100 mM Acetic Acid. Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- IL-2 (IL2) (Interleukin 2 (IL2))
- 别名
- IL-2 (IL2 产品)
- 背景
- Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells.
- 分子量
- The protein has a predicted 15.5 kDa same as Tris-Bis PAGE result.
- UniProt
- P60568
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
-