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Hemopexin Protein (HPX) (AA 24-460) (His tag)

This Recombinant Hemopexin protein is expressed in HEK-293 Cells.
产品编号 ABIN7274828
发货至: 中国

Quick Overview for Hemopexin Protein (HPX) (AA 24-460) (His tag) (ABIN7274828)

抗原

See all Hemopexin (HPX) 蛋白
Hemopexin (HPX)

蛋白类型

Recombinant

宿主

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小鼠

资源

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 24-460

    标记

    This Hemopexin protein is labelled with His tag.

    原理

    Mouse HPX Protein

    序列

    Ser24-Gln460

    产品特性

    Recombinant Mouse HPX Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Gln460.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 50 mM MES, 150 mM NaCl ( pH 6.0).

    缓冲液

    Lyophilized from 0.22μm filtered solution in 50 mM MES, 150 mM NaCl ( pH 6.0). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Hemopexin (HPX)

    别名

    HPX

    背景

    Hemopexin (HPX) serves as scavenger and transporter of toxic plasma heme to the liver. HPX is formed by two four-bladed beta-propeller domains, resembling two thick disks that lock together at a 90 degrees angle. The heme is bound between the two beta-propeller domains in a pocket formed by the interdomain linker peptide.HPX, acting not only as a heme carrier but also displaying transient heme-based ligand binding and (pseudo-)enzymatic properties, could be considered a 'chronosteric' heme-protein.

    分子量

    50 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

    UniProt

    Q91X72

    途径

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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