FGF10 Protein (AA 38-208) (Biotin)
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北京 101111
Quick Overview for FGF10 Protein (AA 38-208) (Biotin) (ABIN7274615)
抗原
See all FGF10 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 38-208
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标记
- This FGF10 protein is labelled with Biotin.
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原理
- Biotinylated Human FGF10 Protein (Primary Amine Labeling)
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序列
- Gln38-Ser208
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产品特性
- Recombinant Biotinylated Human FGF10 Protein (Primary Amine Labeling) is expressed from E.coli without tag.It contains Gln38-Ser208.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Biotinylated Human FGF10, No tag immobilized on CM5 Chip can bind Human FGFR2 alpha IIIb, His tag with an affinity constant of 147.70 nM as determined in SPR assay (Biacore T200) (QC Test).,Biotinylated Human FGF10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Serial dilutions of Anti-FGFR2 alpha (IIIb) Antibody were added into Human FGFR2 alpha (IIIb) , His Tag : Biotinylated Human FGF10, No Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 0.7ng/ml.,The purity of Biotinylated Human FGF10 is greater than 95% as determined by SEC-HPLC.
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Fibroblast Growth Factor 10 (FGF10) (AA 38-208) (Active) protein
FGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by Bis-Tris PAGE Active
Fibroblast Growth Factor 10 (FGF10) (AA 37-215) protein (His-IF2DI Tag)FGF10 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fibroblast Growth Factor 10 (FGF10) (AA 38-137) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) (AA 1-208) protein (GST tag)FGF10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) proteinFGF10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22 μm filtered solution in PBS, 200 mM L-arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- FGF10 (Fibroblast Growth Factor 10 (FGF10))
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别名
- FGF10
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背景
- Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
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分子量
- 19.3 kDa same as Bis-Tris PAGE result.
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UniProt
- O15520
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
抗原
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