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beta-2 Microglobulin Protein (AA 21-119) (His tag)

Name: beta-2 Microglobulin Protein (AA 21-119) (His tag)
Brand: antibodies-online
SKU: ABIN7273887
Availability: OutOfStock

B2M 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Cynomolgus B2M on Tris-Bis PAGE under reduced condition. (beta-2 Microglobulin Protein (AA 21-119) (His tag))

SDS

SEC-HPLC

2 images

产品编号 ABIN7273887

发货至: 中国

Datasheet as PDF

抗原 See all beta-2 Microglobulin (B2M) 蛋白

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

蛋白类型

Recombinant

产品特性

AA 21-119
宿主
15

5

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猕猴, Cynomolgus
资源
48

12

8

3

1

1

1
HEK-293 Cells

标记

This beta-2 Microglobulin protein is labelled with His tag.

原理

Cynomolgus/Rhesus macaque B2M/beta 2-Microglobulin Protein

序列

Ile21-Met119

产品特性

Recombinant Cynomolgus/Rhesus macaque B2M/beta 2-Microglobulin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile21-Met119.

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

过滤

0.22 μm filtered

内毒素水平

Less than 1EU per μg by the LAL method.
beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)
B2M 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

beta-2-Microglobulin (B2M) (AA 21-119) protein (Fc Tag)
B2M 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

beta-2-Microglobulin (B2M) (AA 1-119) protein (GST tag)
B2M 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

beta-2-Microglobulin (B2M) protein
B2M 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS

beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing SDS-PAGE.

beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE.

beta-2-Microglobulin (B2M) (AA 21-119) protein (His tag)
B2M 宿主: 大鼠宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing SDS-PAGE.

beta-2-Microglobulin (B2M) protein
B2M 宿主: 人宿主: Human Native > 98 %

beta-2-Microglobulin (B2M) (AA 1-119) protein (His tag)
B2M 宿主: 小鼠宿主: HEK-293 Cells Recombinant >95 % as determined by reducing SDS-PAGE.

限制

仅限研究用
状态

Lyophilized

溶解方式

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

缓冲液

Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

储存条件

-20 °C,-80 °C

储存方法

-20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

有效期

12 months
抗原

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

别名

B2M (B2M 产品)

背景

The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.

分子量

12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

UniProt

Q8SPW0

途径

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process