Quick Overview for NKG2A & CD94 protein (Fc Tag) (ABIN7271623)
抗原
NKG2A & CD94
蛋白类型
Recombinant
宿主
小鼠
资源
HEK-293 Cells
纯度
>95 % as determined by SDS-PAGE.
标记
Fc Tag
原理
Mouse NKG2A&CD94 Protein, Fc Tag
序列
Thr 95 - Ile 244 (NKG2A) & Ile 32 - Ile 179 (CD94)
产品特性
Mouse NKG2A&CD94, Fc Tag (NC4-M5254) is expressed from human 293 cells (HEK293). It contains AA Thr 95 - Ile 244 (NKG2A) & Ile 32 - Ile 179 (CD94) (Accession # Q9Z202-1 (NKG2A) & O54707-1 (CD94).
宿主: Cynomolgus
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
应用备注
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 61.3 kDa. The protein migrates as 70-80 kDa under reducing (R) condition due to glycosylation.
限制
仅限研究用
状态
Lyophilized
缓冲液
PBS, pH 7.4
储存条件
-20 °C
储存方法
-20°C
抗原
NKG2A & CD94
别名
NKG2A&CD94
背景
Synonyms:NKG2A & CD94,Description:CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.