IgG2 Fc protein (Fc Tag)
In vivo Grade
宿主: 人
宿主: Mammalian Cells
Recombinant
> 95 %
in vivo, IsoC
-
- 抗原
- IgG2 Fc
- 蛋白类型
- Recombinant
- 宿主
- 人
- 资源
- Mammalian Cells
- 标记
- Fc Tag
- 应用范围
- In vivo Studies (in vivo), Isotype Control (IsoC)
- 原理
- In Vivo Grade Recombinant Human IgG2 Fc Protein
- 产品特性
- Human Fc (IgG2) is the tail region of an immunoglobulin G2 (IgG2) that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. The ~230 amino acid fragment generally exists as a dimer, although under reducing conditions, it exists as a monomer. It is the basis of prolonged pharmacokinetics of antibodies and is commonly used as a fusion to extend half-life of fusion proteins. IgG2 has a shorter hinge than IgG1, with 12 amino acid residues and four disulfide bridges at the Fab base. The hinge region of IgG2 also lacks a glycine residue, which along with its shortness almost completely prevents rotation and restricts lateral movement of the Fabs.
- 纯度
- > 95 %
- 过滤
- Sterile filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg)
- 质量等级
- In vivo Grade
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
- 有效期
- 3 months
-
- 抗原
- IgG2 Fc
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