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CD3 epsilon Protein (CD3E) (Biotin)

This Recombinant CD3 epsilon protein is expressed in 人细胞.
产品编号 ABIN7319836
发货至: 中国

Quick Overview for CD3 epsilon Protein (CD3E) (Biotin) (ABIN7319836)

抗原

See all CD3 epsilon (CD3E) 蛋白
CD3 epsilon (CD3E)

蛋白类型

Recombinant

宿主

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资源

  • 22
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人细胞

纯度

>95 % as determined by reducing SDS-PAGE.
  • 标记

    This CD3 epsilon protein is labelled with Biotin.

    原理

    Recombinant Human CD3 epsilon/CD3E (C-Fc-Avi) Biotinylated

    序列

    Asp23-Asp126

    产品特性

    Biotinylated Recombinant Human T-cell Surface Glycoprotein CD3 Epsilon Chain is produced by our Mammalian expression system and the target gene encoding Asp23-Asp126 is expressed with a Fc, Avi tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 说明

    45-60 kDa

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3E

    背景

    Background: T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3ε is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

    Synonym: T-Cell Surface Glycoprotein CD3 Epsilon Chain, T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e, CD3E, T3E

    分子量

    40.5 kDa

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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