Quick Overview for FGF8 蛋白 (ABIN7198878)
抗原
See all FGF8 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human FGF8a/FGF-8a Protein (Active)
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序列
- Gln23-Arg204
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产品特性
- A DNA sequence encoding the human FGF8a (NP_149355.1) (Gln23-Arg204) was expressed with an initial Met.
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内毒素水平
- Please contact us for more information.
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Biological Activity Comment
- Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.8-3.3 μg/mL.
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Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 23-215) (Active) protein
FGF8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (Active) proteinFGF8 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 53-233) protein (His tag)FGF8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (AA 23-215) protein (His tag)FGF8 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.5
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
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别名
- FGF8a
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背景
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Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Synonym: AIGF,FGF-8,HBGF-8,HH6,KAL6
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分子量
- 21.3 kDa
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NCBI登录号
- NP_149355
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
抗原
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