Vinculin Protein (VCL)
Quick Overview for Vinculin Protein (VCL) (ABIN7319171)
抗原
See all Vinculin (VCL) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human VCL/Vinculin Protein
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序列
- Pro2-Gln1066
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产品特性
- Recombinant Human Vinculin is produced by our E.coli expression system and the target gene encoding Pro2-Gln1066 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Vinculin (VCL) (AA 2-235) protein (His tag)
VCL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Vinculin (VCL) (AA 777-1066) protein (GST tag)VCL 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Vinculin (VCL) (AA 1-1066) protein (GST tag)VCL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vinculin (VCL) protein (His tag)VCL 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Vinculin (VCL) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)VCL 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Vinculin (VCL)
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别名
- VCL/Vinculin
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背景
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Background: Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/α-Catenin family. Vinculin is an Actin-binding protein and component of the Actin-Linking Functional module that senses and feels the mechanical properties of the extracellular environment. Vinculin is also a key factor that couples, transmits, transduces, and regulates mechanical force between the cytoskeleton and adhesion receptors. Vinculin generally forms two structural states, an open (active) and closed (inactive) state, which are controlled by conformational interaction(s) between the head and tail domains. Vinculin is involved in the mechano-chemical signal transmission of cells by binding to a variety of focal adhesion or cytoskeletal proteins, and plays important roles in cell adhesion, extension, motion, proliferation and survival.
Synonym: Vinculin, Metavinculin, VCL,CMD1W,CMH15,HEL114,MV,MVCL
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分子量
- 117.0 kDa
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UniProt
- P18206
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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