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Vinculin Protein (VCL) (His tag)

This Recombinant Vinculin protein is expressed in HEK-293 Cells.
产品编号 ABIN7318069
发货至: 中国
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Quick Overview for Vinculin Protein (VCL) (His tag) (ABIN7318069)

抗原

See all Vinculin (VCL) 蛋白
Vinculin (VCL)

蛋白类型

Recombinant

宿主

  • 11
  • 2

资源

  • 10
  • 2
  • 1
HEK-293 Cells

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 标记

    This Vinculin protein is labelled with His tag.

    原理

    Recombinant Human VCL/Vinculin Protein (His Tag)

    序列

    Met 1-Gln 1066

    产品特性

    A DNA sequence encoding the human VCL (P18206-2) (Met 1-Gln 1066) was expressed, fused with a polyhistidine tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Vinculin (VCL)

    别名

    VCL/Vinculin

    背景

    Background: Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.

    Synonym: Vinculin, Metavinculin, VCL,CMD1W,CMH15,HEL114,MV,MVCL

    分子量

    118 kDa

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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