UNG Protein (GST tag)
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- 抗原 See all UNG 蛋白
- UNG (Uracil-DNA Glycosylase (UNG))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This UNG protein is labelled with GST tag.
- 原理
- Recombinant Human Uracil-DNA glycosylase/UNG Protein (GST Tag)
- 序列
- Phe 85-Leu 304
- 产品特性
- A DNA sequence encoding the human UNG isoform 1 (P13051-2) (Phe 85-Leu 304) was fused with the GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UNG 蛋白
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Uracil-DNA Glycosylase (UNG) (AA 86-190) protein (GST tag)
UNG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Uracil-DNA Glycosylase (UNG) (AA 1-304) protein (GST tag)UNG 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Uracil-DNA Glycosylase (UNG) (AA 1-313) protein (Strep Tag)Crystallography grade UNG 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Uracil-DNA Glycosylase (UNG) (AA 1-229) protein (His tag)UNG 宿主: E. coli 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Uracil-DNA Glycosylase (UNG) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)UNG 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 40 mM Tris, 0.15M NaCl, 2 mM GSH, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- UNG (Uracil-DNA Glycosylase (UNG))
- 别名
- Uracil-DNA glycosylase/UNG (UNG 产品)
- 别名
- DGU Protein, HIGM4 Protein, HIGM5 Protein, UDG Protein, UNG1 Protein, UNG15 Protein, UNG2 Protein, ung Protein, zgc:56102 Protein, PSPTO4236 Protein, BA5648 Protein, ECK2578 Protein, JW2564 Protein, An02g14790 Protein, AO090001000732 Protein, DDBDRAFT_0204444 Protein, DDBDRAFT_0214910 Protein, DDB_0204444 Protein, DDB_0214910 Protein, uracil-DNA glycosylase Protein, uracil DNA glycosylase Protein, uracil DNA glycosylase a Protein, uracil-DNA glycosylase Ung Protein, uracil-DNA-glycosylase Protein, uracil DNA glycosylase L homeolog Protein, uracil glycosylase Protein, temporal expression: early Protein, ung Protein, ung2 Protein, Ung Protein, UNG Protein, unga Protein, STY2840 Protein, ung.L Protein, ANI_1_3358024 Protein, AOR_1_1318164 Protein, uglA Protein, Arnit_2731 Protein, D4R Protein
- 物质类
- Viral Protein
- 背景
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Background: Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in two forms: mitochondrial uracil-DNA glycosylase 1 (UNG1) and nuclear uracil-DNA glycosylase 2 (UNG2). uracil-DNA glycosylase. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.
Synonym: DGU,HIGM4,HIGM5,UDG,UNG1,UNG15,UNG2
- 分子量
- 52 kDa
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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