TWSG1 Protein (His tag)
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- 抗原 See all TWSG1 蛋白
- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This TWSG1 protein is labelled with His tag.
- 原理
- Recombinant Human TWSG1/TSG Protein (His Tag)
- 序列
- Cys26-Phe223
- 产品特性
- Recombinant Human Twisted Gastrulation Protein Homolog 1 is produced by our Mammalian expression system and the target gene encoding Cys26-Phe223 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TWSG1 蛋白
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Twisted Gastrulation Homolog 1 (TWSG1) (AA 1-223) protein (GST tag)
TWSG1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
- 别名
- TWSG1/TSG (TWSG1 产品)
- 背景
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Background: Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to BMP proteins, and can act the anti-BMP function, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. TWSG1 may be an important modulator of BMP-regulated cartilage development, chondrocyte differentiation and thymocyte development.
Synonym: Twisted Gastrulation Protein Homolog 1, TWSG1, TSG
- 分子量
- 23.2 kDa
- UniProt
- Q9GZX9
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