TGFB3 蛋白
Quick Overview for TGFB3 蛋白 (ABIN7319107)
抗原
See all TGFB3 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human TGFB3 Protein (Active)
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序列
- Ala301-Ser412(Tyr340Phe)
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产品特性
- Recombinant Human/Mouse Transforming Growth Factor beta 3 is produced by our Mammalian expressionsystem and the target gene encoding Ala301-Ser412(Tyr340Phe) is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 10-80 pg/ml.
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Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) protein
TGFB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) protein (AVI tag,Biotin)TGFB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Transforming Growth Factor, beta 3 (TGFB3) (Active) proteinTGFB3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Transforming Growth Factor, beta 3 (TGFB3) (AA 1-412) protein (GST tag)TGFB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transforming Growth Factor, beta 3 (TGFB3) (AA 24-412) protein (His tag)TGFB3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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别名
- TGFB3
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背景
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Background: Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3 becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3, mammals develop a deformity known as a cleft palate.
Synonym: Transforming growth factor beta-3,TGFB3,TGF-beta-3,Latency-associated peptide,LAP
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分子量
- 12.7 kDa
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UniProt
- P10600
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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