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TGFB2 蛋白

This Recombinant TGFB2 protein is expressed in 人细胞.
产品编号 ABIN7319106
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TGFB2 蛋白 (ABIN7319106)

抗原

See all TGFB2 蛋白
TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human TGFB2 Protein (Active)

    序列

    Ala303-Ser414

    产品特性

    Recombinant Human Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.

    Biological Activity Comment

    Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 0.3-1.5 ng/ml.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

    别名

    TGFB2

    背景

    Background: Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).

    Synonym: Transforming growth factor beta-2,TGFB2,Polyergin,G-TSF,Glioblastoma-derived T-cell suppressor factor,Cetermin,BSC-1 cell growth inhibitor,TGF-beta-2

    分子量

    12.7 kDa

    UniProt

    P61812

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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