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Quick Overview for TCN2 Protein (His tag) (ABIN7198283)
抗原
See all TCN2 蛋白蛋白类型
宿主
资源
纯度
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标记
- This TCN2 protein is labelled with His tag.
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原理
- Recombinant Mouse TCN2 Protein (His Tag)
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序列
- Met 1-Trp 430
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产品特性
- A DNA sequence encoding the mouse TCN2 (O88968) (Met 1-Trp 430) was expressed, with a C-terminal polyhistidine tag.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Transcobalamin II (TCN2) (AA 1-400) protein (GST tag)
TCN2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Transcobalamin II (TCN2) (AA 20-427) protein (GST tag)TCN2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TCN2 (Transcobalamin II (TCN2))
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别名
- TCN2
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背景
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Background: Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl, vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin complex binds to receptors on the plasma membrane of tissue cells and is then internalized by receptor-mediated endocytosis. Transcobalamin II is a non-glycolated secretory protein of molecular mass 43 kDa. Its plasma membrane receptor (TC II-R) is a heavily glycosylated protein with a monomeric molecular mass of 62 kDa. Human TCN2 gene is composed of nine exons and eight introns spanning approximately 20 kb with multiple potential transcription start sites. A number of genetic abnormalities are characterized either by a failure to express TCN2 or by synthesis of an abnormal protein. The TCN2 deficiency results in cellular cobalamin deficiency, an early onset of megaloblastic anaemia, and neurological abnormalities.
Synonym: AW208754,Tcn-2
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分子量
- 47 kDa
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UniProt
- O88968
抗原
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