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Syndecan 1 Protein (SDC1) (His tag)

This Recombinant Syndecan 1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7320206
发货至: 中国

Quick Overview for Syndecan 1 Protein (SDC1) (His tag) (ABIN7320206)

抗原

See all Syndecan 1 (SDC1) 蛋白
Syndecan 1 (SDC1)

蛋白类型

Recombinant

宿主

  • 24
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小鼠

资源

  • 18
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HEK-293 Cells

纯度

> 80 % as determined by SDS-PAGE
  • 标记

    This Syndecan 1 protein is labelled with His tag.

    原理

    Recombinant Mouse Syndecan-1/SDC1 Protein (His Tag)

    序列

    Met 1-Glu 252

    产品特性

    A DNA sequence encoding the extracellular domain of mouse SDC1 (NP_035649.1) (Met 1-Glu 252) was expressed, with a C-terminal polyhistidine tag.

    内毒素水平

    < 1.0 EU per μg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    Syndecan 1 (SDC1)

    别名

    Syndecan-1/SDC1

    背景

    Background: Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.

    Synonym: AA408134,AA409076,CD138,Sstn,syn-1,Synd,Synd1

    分子量

    26 kDa

    NCBI登录号

    NP_035649

    途径

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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