SPHK1 蛋白
Quick Overview for SPHK1 蛋白 (ABIN7317043)
抗原
See all SPHK1 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (Active)
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序列
- Met 1-Leu 384
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产品特性
- A DNA sequence encoding the human SPHK1 (Q9NYA1-1)(Met1-Leu384) was fused with two additional amino acids (Gly & Pro) at the N-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 1028 nmol/min/mg using Sphingosine Kinase Substrate as substrate.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 98,872.65 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 132,714.14 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (His tag)
custom-made SPHK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sphingosine Kinase 1 (SPHK1) (AA 1-382) protein (His tag)custom-made SPHK1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Sphingosine Kinase 1 (SPHK1) (AA 1-384) protein (GST tag)SPHK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Sphingosine Kinase 1 (SPHK1) protein (GST tag,His tag)SPHK1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Sphingosine Kinase 1 (SPHK1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SPHK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Frozen, Liquid
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缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1/Sphingosine Kinase 1
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背景
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Background: SPHK1, also known as sphingosine Kinase 1, catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P). S1P exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes.
Synonym: SPHK,SPHK1,SPK
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分子量
- 42.7 kDa
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途径
- VEGF Signaling
抗原
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