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SIGLEC5 蛋白

This Recombinant SIGLEC5 protein is expressed in HEK-293 Cells.
产品编号 ABIN7317484
发货至: 中国

Quick Overview for SIGLEC5 蛋白 (ABIN7317484)

抗原

See all SIGLEC5 蛋白
SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

蛋白类型

Recombinant

宿主

  • 18
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资源

  • 8
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HEK-293 Cells

纯度

> 85 % as determined by reducing SDS-PAGE.
  • 原理

    Recombinant Human SIGLEC5 Protein

    序列

    Met 1-Thr 434

    产品特性

    A DNA sequence encoding the human SIGLEC5 (O15389) (Met1-Thr 434) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))

    别名

    SIGLEC5

    背景

    Background: SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

    Synonym: Sialic acid-binding Ig-like lectin 5, Siglec-5, CD33 antigen-like 2, Obesity-binding protein 2, OB-BP2, CD170,CD33L2,OB-BP2,OBBP,OBBP2,SIGLEC-5,SIGLEC5

    分子量

    47.2 kDa

    UniProt

    O15389
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