Quick Overview for SPINK4 Protein (Fc Tag) (ABIN7320100)
抗原
See all SPINK4 蛋白蛋白类型
宿主
资源
纯度
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标记
- This SPINK4 protein is labelled with Fc Tag.
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原理
- Recombinant Mouse SPINK4 Protein (Fc Tag)
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序列
- Met 1-Cys 86
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产品特性
- A DNA sequence encoding the mouse SPINK4 (NP_035593.2) (Met 1-Cys 86) was fused with the Fc region of human IgG1 at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SPINK4 (Serine Peptidase Inhibitor, Kazal Type 4 (SPINK4))
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别名
- SPINK4
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背景
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Background: Serine protease inhibitor Kazal-type 4, also known as Peptide PEC-60 homolog and SPINK4, is a secreted protein which contains one Kazal-like domain. SPINK4 is a member of the SPINK protein family. The gene family of serine protease inhibitors of the Kazal type (SPINK) are functional and positional candidate genes for celiac disease (CD). SPINK1 plays an important role in protecting the pancreas against excessive trypsinogen activation. It is a potent natural inhibitor of pancreatic trypsin activity. SPINK1 mutations are associated with the development of acute and chronic pancreatitis and have been detected in all forms of chronic pancreatitis. SPINK2 functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. SPINK9 was identified in human skin. Its expression was strong in palmar epidermis, but not detectable or very low in non palmoplantar skin.
Synonym: MPGC60,RP23-28I8.2
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分子量
- 34.5 kDa
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NCBI登录号
- NP_035593
抗原
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